增加局部血管直径和血流量,增强胰岛素吸收




该评价包括18篇文章，其中大多数指向LLLT方向对局部循环有显着影响; 增加血管舒张，血流量和灌注。 与对照餐相比，概念验证研究在用餐开始后的头两个小时的葡萄糖曲线下导致统计学上显着更小的面积（p = 0.003），并且当峰值葡萄糖水平显着提前达到时。 使用了装置（p = 0.034）。 然而，在前半小时和小时的葡萄糖曲线下面积之间，最大斜率或在膳食之间达到半峰值葡萄糖值的时间之间没有统计学上显着的差异。

结论：系统性文献综述清楚地表明LLLT具有增加局部血管直径和血流量的潜力。 概念验证研究的结果表明，LLLT还可增强餐时胰岛素大丸剂的吸收，

 often resulting in a delayed peak and a prolonged duration of action, increasing
the risk of early post prandial hyperglycemia and late … 
Results: The review included 18 articles, where the majority points in the direction of LLLT having a significant effect on the local circulation; increasing vasodilation, blood flow, and perfusion. The proof of concept study resulted in a statistically significantly smaller area under the glucose curve for the first two hours after meal start for the Anodyne® meals compared with the control meals (p=0.003), and peak glucose level was reached significantly earlier when the device was used (p=0.034). There were, however, no statistically significant difference between the areas under the glucose curve for the first half hour and hour, maximum slope or time to half peak glucose value between the meals.
Conclusion: The systematic literature review clearly indicates that LLLT has the potential to increase local vessel diameter and blood flow. The results from the proof of concept study indicate that LLLT also enhances the absorption of prandial insulin boluses,

Finne, Solveig Nyland. Enhancement of Insulin Absorption by Local Manipulation of the Site of Injection. MS thesis. NTNU, 2019.

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