LLLT

在許多情況下，也觀察到不自主運動的加重和頸部和背部的疼痛。 現有的保守治療方法已證明或多或少無效，成人功能訓練的局限性使得治療極為困難。 我們在1994年首次採用低反應激光治療（LLLT）治療痙攣性腦癱，效果良好。 在本研究中，我們對20名患有成人緊張性手足徐動症的腦癱患者的肌無力嚴重的面部和頸部區域的所有肌強直部位應用激光照射（830 nm，60 mW連續波），但沒有效果 治療頸部和背部疼痛。 失眠和排尿困難也有所改善。 即使在最嚴重的情況下，協助患者變得更容易，呼吸也得到改善。 使用830 nm二極管激光器的LLLT在這個極其成問題的情況下提供了一種新的有效治療方式 Insomnia  and dysuria also improved. Even in the most severe cases, assisting the patient became easier and breathing improved.  LLLT  with the 830 nm diode laser provides a new and effective treatment modality in this extremely problematic condition, has no serious side   Aggravation of involuntary movements and pain in the neck and back are also seen in many cases. Existing conservative treatment methodologies have proved to be more or less ineffective, and limitations in functional training in adults have made treatment extremely difficult. We first employed low reactive-level laser therapy (LLLT) in a case of spastic cerebral palsy in 1994 with good results. In the presen...

该评价包括18篇文章，其中大多数指向LLLT方向对局部循环有显着影响; 增加血管舒张，血流量和灌注。 与对照餐相比，概念验证研究在用餐开始后的头两个小时的葡萄糖曲线下导致统计学上显着更小的面积（p = 0.003），并且当峰值葡萄糖水平显着提前达到时。 使用了装置（p = 0.034）。 然而，在前半小时和小时的葡萄糖曲线下面积之间，最大斜率或在膳食之间达到半峰值葡萄糖值的时间之间没有统计学上显着的差异。 结论：系统性文献综述清楚地表明LLLT具有增加局部血管直径和血流量的潜力。 概念验证研究的结果表明，LLLT还可增强餐时胰岛素大丸剂的吸收， often resulting in a delayed peak and a prolonged duration of action, increasing the risk of early post prandial  hyperglycemia  and late …  Results: The review included 18 articles, where the majority points in the direction of LLLT having a significant effect on the local circulation; increasing vasodilation, blood flow, and perfusion. The proof of concept study resulted in a statistically significantly smaller area under the glucose curve for the first two hours after meal start for the Anodyne® meals compared with the control meals (p=0.003), and peak glucose level was reached significantly earlier when the device was used (p=0.034). There were, however, no statistically significant...

該研究調查了三種微創手術，即激光耳廓療法（LAT），磁性耳廓療法（MAT）及其組合。使用了七個耳穴。治療每週進行三次，持續六週。在基線，六周和六週，三個月和六個月後的隨訪評估受試者。基於匹茲堡睡眠質量指數（PSQI），使用活動記錄監測的睡眠參數，使用SF-12的健康相關生活質量（HRQOL）和抑鬱症的PHQ-9，使用廣義估計方程來評估各組之間的相互作用。 三種方法的治療效果相當。隨著時間的推移，各個群體的所有主觀測量（PSQI，HRQOL和PHQ-9）均有顯著改善。在接受MAT程序但未接受LAT治療的受試者中檢測到使用活動記錄監測的客觀睡眠參數的改善。 This study investigated three minimally invasive procedures, namely, laser auriculotherapy (LAT), magneto-auriculotherapy (MAT), and their combination. Seven auricular points were used. Treatment was performed three times a week, for six weeks. Subjects were assessed at baseline, six weeks, and follow-up after six weeks, three months, and six months. Generalised estimating equations were used to evaluate interactions amongst the groups over time based on the Pittsburgh Sleep Quality Index (PSQI), sleep parameters using actigraphic monitoring, health-related quality of life (HRQOL) using SF-12, and PHQ-9 for depression status.  Results . The treatment effects of the three procedures were comparable. Si...

LLLT可用作CABG手术后术后疼痛控制的非侵入性，易于应用，有效且安全的辅助治疗方式。 然而，进一步的精心设计研究有必要确定和确认LLLT在CABG手术后术后疼痛管理的潜在临床价值，以及其功效密度，波长，脉冲结构和影响/时间等参数的最佳选择。 辐射，可以影响这种治疗方式的有效性。 The results of a study by Fernandes et al. [ 7 ] showed the efficacy of LLLT (wavelength-660 nm) in reducing the acute postoperative pain of sternotomy after CABG surgery. In this study, patients' mean visual analogue scale (VAS) scores reduced from 6, in the second day, to 1.5 in the eighth day after surgery. Another study by Lima et al. [ 8 ] revealed the positive analgesic effect of LLLT (wavelength-640 nm) in hyperglycemic and normoglycemic patients who underwent CABG surgery (patients' mean VAS scores decreased significantly from 6 to 2 in the second and eighth day after surgery, respectively). In these two studies, patients received LLLT immediately after surgery and on subsequent days 2, 4, 6, and 8, postoperatively. A study by Karlekar et al. [ 9 ] found that laser therapy (wavelength-980 nm) in the postoperative peri...

仅在高葡萄糖培养基中培养的HGF显示出促炎细胞因子的显着高于与LLLI一起处理的那些。 然后我们观察到LLLI通过调节cAMP信号传导降低了在高葡萄糖培养基中培养的HGF中促炎细胞因子的表达。 我们还研究了抗氧化剂（维生素C）处理是否降低了在高葡萄糖培养基中培养的HGF中氧化应激的炎症效应，但是发现LLLI与LLLI共同处理没有添加效应，这表明LLLI可能激活cAMP信号传导，但不激活活性氧物质 （ROS）信号传导，以减少高葡萄糖诱导的炎症。 总之，LLLI可能在高葡萄糖环境中对HGF具有抗炎作用 HGFs cultured only in high-glucose medium showed significantly higher expression of pro-inflammatory cytokine than in those treated together with LLLI. We then observed that LLLI reduced the expression of pro-inflammatory cytokines in HGFs cultured in high-glucose medium by modulating cAMP signaling. We also investigated whether antioxidant (vitamin C) treatment reduced the inflammatory effect of oxidative stress in HGFs cultured in high-glucose medium but found no additive effect upon co-treatment with LLLI, suggesting that LLLI may activate cAMP signaling, but not reactive oxygen species (ROS) signaling, to reduce the high glucose-induced inflammation. In conclusion, LLLI may have an anti-inflammatory effect on HGFs in a high g...

遵循ESMO指南進行疼痛評估和治療可以對輕度，中度和重度癌症疼痛的治療有顯著幫助[18]。 低水平激光治療是一種廣泛發展的策略，用作癌症患者的輔助治療。 LLLT減輕疼痛（嚴重程度，強度和持續時間），炎症，腫脹，淋巴水腫，與放療和化療相關的疼痛相關的不良反應，如粘膜炎疼痛和皮膚病學病理，並具有鎮痛，抗炎和生物刺激作用[19-21]。 LLLT最初在表皮神經網絡水平具有直接作用，然後移動到皮下組織的神經 Following the ESMO-guidelines for pain assessment and treatment could of significant help in management of mild, moderate, and severe cancer pain [18]. Low-level laser therapy is a widely evolving strategy used as an adjunct therapy in cancer patients. LLLT reduces the pain (severity, intensity, and duration), inflammation, swelling, lymphedema, and adverse effects related pain of radiotherapy and chemotherapy such as pain in mucositis and dermatological pathologies in patients and have analgesic, anti-inflammatory and bio stimulating effects [19-21]. LLLT initially has a direct effect at the epidermal neural network level and then moves to the nerves in subcutaneous tissues Vernucci, E., S. Agrawal, and V. Rai. "Role of Multidisciplinary Approach in the Management of Cancer...