radiation induced OM

如果嚴重的OM在放療期間發生得足夠早,或者如果延長或變得更加嚴重,則需要積極的管理

其中LLLT對老年患者的輻射誘導OM有影響...許多這些研究是在兒科和成人人群中進行的,但到目前為止,沒有一項研究專門評估接受RT治療的老年人的影響。
與安慰劑組相比,在激光中觀察到嚴重OM(p = 0.016)和嚴重疼痛(p = 0.023)和體重減輕(p = 0.004)的發生率和持續時間的顯著降低。 降低老年HNC患者的OM和口腔疼痛的嚴重程度。
where LLLT effects against radiation induced OM in elderly patients … Many of these studies were done on the pediatric and adult population, but until now none of the studies have specifically evaluated the effects in elderly people receiving RT 
Significant reduction in the incidence and duration of severe OM (p = 0.016) and severe pain (p = 0.023) and weight loss (p = 0.004) was observed in laser than placebo group. No difference was found for enteral feeding use (p = 0.667) between two groups.

Gautam, Ajay Prashad, et al. "Low level laser therapy against radiation induced oral mucositis in elderly head and neck cancer patients-a randomized placebo controlled trial." Journal of Photochemistry and Photobiology B: Biology 144 (2015): 51-56.


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