120名志愿者接受了选择性冠状动脉旁路移植术（CABG）手术。 志愿者被随机分配到四个相同大小（n = 30）的不同组：对照组，安慰剂组，LLLT [λ= 640 nm和空间平均能量注量（SAEF）= 1.06 J / cm（2）]和LED（λ） = 660±20nm，SAEF = 0.24J / cm（2））。 根据手术前的空腹血糖测试结果，参与者也被分为高血糖和血糖正常的亚组。 评估的结果是通过视觉模拟量表（VAS）和McGill疼痛问卷进行咳嗽时的疼痛。
结果：
手术后患者随访1个月。 与安慰剂组和对照组相比，LLLT和LED组在术后第6天和第8天与VAS和McGill问卷（p≤0.05）相比，疼痛减轻更多，结果相似。

Low-Level Laser and Light-Emitting Diode Therapy for Pain Control in Hyperglycemic and Normoglycemic Patients Who Underwent Coronary Bypass Surgery with Internal Mammary Artery Grafts: A Randomized, Double-Blind Study with Follow-Up.

120 volunteers who underwent elective coronary artery bypass graft (CABG) surgery. The volunteers were randomly allocated to four different groups of equal size (n = 30): control, placebo, LLLT [λ = 640 nm and spatial average energy fluence (SAEF) = 1.06 J/cm(2)], and LED (λ = 660 ± 20 nm and SAEF = 0.24 J/cm(2)). Participants were also divided into hyperglycemic and normoglycemic subgroups, according to their fasting blood glucose test result before surgery. The outcome assessed was pain during coughing by a visual analog scale (VAS) and the McGill Pain Questionnaire.

RESULTS:

The patients were followed for 1 month after the surgery. The LLLT and LED groups showed a greater decrease in pain, with similar results, as indicated by both the VAS and the McGill questionnaire (p ≤ 0.05), on the 6th and 8th postoperative day compared with the placebo and control groups. 

 2016 Jun;34(6):244-51. doi: 10.1089/pho.2015.4049. Epub 2016 Apr 15.

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