脉络膜骨瘤



激光照射使组织吸收的光敏剂受到激发,而激发态的光敏剂又把能量传递给周围的氧,生成活性很强的单态氧,单态氧和相邻的生物大分子发生氧化反应,产生细胞毒性作用,进而导致细胞受损乃至死亡,作为一种对RPE 层的依赖性较小物理疗法,目前也运用于治疗继发于脉络膜骨瘤的CNV 患者。现有研究报道证实PDT 治疗黄斑中心凹[26] 及中心凹外[22] 的CNV均取得了较好的疗效。PDT 疗法在短期内可加速CNV 的消退,但是可能需要进行多个疗程,治疗次数的增加将会使患者的最终视力下降。



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在高葡萄糖环境中对HGF具有抗炎作用

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仅在高葡萄糖培养基中培养的HGF显示出促炎细胞因子的显着高于与LLLI一起处理的那些。 然后我们观察到LLLI通过调节cAMP信号传导降低了在高葡萄糖培养基中培养的HGF中促炎细胞因子的表达。 我们还研究了抗氧化剂（维生素C）处理是否降低了在高葡萄糖培养基中培养的HGF中氧化应激的炎症效应，但是发现LLLI与LLLI共同处理没有添加效应，这表明LLLI可能激活cAMP信号传导，但不激活活性氧物质 （ROS）信号传导，以减少高葡萄糖诱导的炎症。 总之，LLLI可能在高葡萄糖环境中对HGF具有抗炎作用 HGFs cultured only in high-glucose medium showed significantly higher expression of pro-inflammatory cytokine than in those treated together with LLLI. We then observed that LLLI reduced the expression of pro-inflammatory cytokines in HGFs cultured in high-glucose medium by modulating cAMP signaling. We also investigated whether antioxidant (vitamin C) treatment reduced the inflammatory effect of oxidative stress in HGFs cultured in high-glucose medium but found no additive effect upon co-treatment with LLLI, suggesting that LLLI may activate cAMP signaling, but not reactive oxygen species (ROS) signaling, to reduce the high glucose-induced inflammation. In conclusion, LLLI may have an anti-inflammatory effect on HGFs in a high g...
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治療痙攣性腦癱

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在許多情況下，也觀察到不自主運動的加重和頸部和背部的疼痛。 現有的保守治療方法已證明或多或少無效，成人功能訓練的局限性使得治療極為困難。 我們在1994年首次採用低反應激光治療（LLLT）治療痙攣性腦癱，效果良好。 在本研究中，我們對20名患有成人緊張性手足徐動症的腦癱患者的肌無力嚴重的面部和頸部區域的所有肌強直部位應用激光照射（830 nm，60 mW連續波），但沒有效果 治療頸部和背部疼痛。 失眠和排尿困難也有所改善。 即使在最嚴重的情況下，協助患者變得更容易，呼吸也得到改善。 使用830 nm二極管激光器的LLLT在這個極其成問題的情況下提供了一種新的有效治療方式 Insomnia  and dysuria also improved. Even in the most severe cases, assisting the patient became easier and breathing improved.  LLLT  with the 830 nm diode laser provides a new and effective treatment modality in this extremely problematic condition, has no serious side   Aggravation of involuntary movements and pain in the neck and back are also seen in many cases. Existing conservative treatment methodologies have proved to be more or less ineffective, and limitations in functional training in adults have made treatment extremely difficult. We first employed low reactive-level laser therapy (LLLT) in a case of spastic cerebral palsy in 1994 with good results. In the presen...
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增加局部血管直径和血流量,增强胰岛素吸收

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该评价包括18篇文章，其中大多数指向LLLT方向对局部循环有显着影响; 增加血管舒张，血流量和灌注。 与对照餐相比，概念验证研究在用餐开始后的头两个小时的葡萄糖曲线下导致统计学上显着更小的面积（p = 0.003），并且当峰值葡萄糖水平显着提前达到时。 使用了装置（p = 0.034）。 然而，在前半小时和小时的葡萄糖曲线下面积之间，最大斜率或在膳食之间达到半峰值葡萄糖值的时间之间没有统计学上显着的差异。 结论：系统性文献综述清楚地表明LLLT具有增加局部血管直径和血流量的潜力。 概念验证研究的结果表明，LLLT还可增强餐时胰岛素大丸剂的吸收， often resulting in a delayed peak and a prolonged duration of action, increasing the risk of early post prandial  hyperglycemia  and late …  Results: The review included 18 articles, where the majority points in the direction of LLLT having a significant effect on the local circulation; increasing vasodilation, blood flow, and perfusion. The proof of concept study resulted in a statistically significantly smaller area under the glucose curve for the first two hours after meal start for the Anodyne® meals compared with the control meals (p=0.003), and peak glucose level was reached significantly earlier when the device was used (p=0.034). There were, however, no statistically significant...
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